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Due to the long duration of diabetes, T2D patients have higher risks of macrovascular and microvascular damage, as well as other severe complications, such as diabetic nephropathy, diabetic cardiomyopathy, non-alcoholic fatty liver disease (NAFLD), diabetic retinopathy, cognitive impairment, that cause mortality (Gregg et al., 2014)

In conclusion, the degree to which GLP-1RAs cross the BBB is determined by a complex interplay of molecular and physicochemical factors

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This is the very first of the bruise healing stages and indicates fresh blood pooling under the skin