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Setting realistic expectations is crucial: weight loss is gradual, with clinical trials showing approximately 15% weight reduction with semaglutide 2.4 mg at 68 weeks and up to 21% with tirzepatide at 72 weeks, though individual responses vary considerably

For millions of frustrated dieters, GLP - 1 drugs might seem like an almost magical solution

David Merrill, MD, PhD, an adult and geriatric psychiatrist and director of the Pacific Neuroscience Institutes Pacific Brain Health Center in Santa Monica, CA, told Healthline

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