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The authors conclude that GLP-1 functions as "a central node linking gut microbiota, metabolic homeostasis, tissue repair, and immune regulation," a framing that positions GLP-1 pathway intervention not as a metabolic adjunct but as a legitimate disease-modifying strategy across the spectrum of age-related musculoskeletal degeneration
The primary symptom is fatigue, often accompanied by pale skin, cold hands and feet, and breathlessness during mild exertion
