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GLP-1 and pancreatic cells (glucose hemostasis, cellular apoptosis, and inflammation) The anti-inflammatory roles of GLP-1 in DM have been investigated through animal studies, which shows that regardless of GLP-1 effects on glycemic control and weight loss, it reduces the pro-inflammatory cytokines such as TNF- and IL-1 [27]

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After a standardized meal test, the L

Some preclinical studies suggest GLP-1 signaling may have anti-inflammatory potential through intestinal barrier protection, while others indicate that rapid changes in gut motility could stress an already inflamed mucosa