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No dose adjustments are recommended for patients with renal impairment

GLP-1 receptor agonists in either form share the class boxed warning for thyroid C-cell tumor risk observed in rodent studies

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Ethics declarations Ethics approval and consent to participate All animal experiments in this study were carried out in conformity with the Guidelines for the Use and Care of Laboratory Animals of the National Institutes of Health and were approved by the Institutional Animal Care and Use Committee (IACUC) of Nanjing Medical University (IACUC-2306028)