semaglutide heart Long-Term SELECT Trial: Cuts Cardiovascular Events by 20% beyond Weight Loss Semaglutide: What impact does it
Description
Importantly, emerging evidence suggests that combination therapy with GLP-1 RAs and SGLT2is may provide synergistic benefits, producing greater reductions in body weight, glycated hemoglobin (HbA1c), and potentially liver-related endpoints compared with either therapy alone
10.1056/NEJMoa2301972 36 JastreboffA
The mechanism is well understood and supported by scientific literature: 1
Results showed that after 72 weeks, participants on tirzepatide experienced significant weight loss: 15.0% with 5 mg, 19.5% with 10 mg, and 20.9% with 15 mg, compared to a 3.1% weight loss with the placebo
