glp-1 prescriptions growth q1 2025 Harvard Business Review | A PwC analysis shows that medications like Ozempic and Zepbound may be catalyzing a behavioral and economic shift on par with major GLP-1 RA prescription trends: January

The personal and psychological changes people experience using GLP-1s are frequently unexpected

They are also said to curb hunger and slow the emptying of the stomach, so you feel full faster and longer, causing you to eat less

Common complaints include nausea, vomiting, and sometimes diarrhea or constipation

Additional extrahypothalamic sites of GLP1 action The role of the GLP1 system for energy balance extends beyond the hypothalamus with both local GLP1 neuronal projections within the dorsal vagal complex and more extensive projections to the midbrain, mesolimbic ventral tegmental area and the nucleus accumbens in the regulation of eating (Alhadeff et al., 2012, 2014