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And the addressable population is about to expand significantly further, because the FDA approved the first oral GLP-1 formulation at the end of 2025, removing the barrier of weekly injections that has kept many potential users from starting treatment

Beyond their metabolic benefits, GLP-1RAs demonstrate immunomodulatory effects, including attenuation of systemic inflammation and modulation of immune cell activity, raising the possibility of relevance to autoimmune conditions such as AITD [9]

Can You Use Semaglutide with Graves' Disease

Clinical trials have shown that semaglutide can produce a 1015% reduction in body weight, results that were once only associated with bariatric surgery