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[PMC free article: PMC11485243] [PubMed: 38914124] 327

A real-world prospective study of 105 patients who completed 12 months of GLP-1RA therapy found that those transitioning to generic medications with a weight-lowering effect maintained a mean total weight loss of 25.5% at approximately 593 days, with metformin being utilised in 80% of this cohort

Senator Bernie Sanders warned in a May 2024 report that the outrageously high prices of these drugs have the potential to bankrupt our entire health care system. An employer survey found that 43% of employers plan to cover weight loss drugs in 2024, doubling the share of employers reporting such coverage in 2023 (25%)

Relative to glimepiride (sulfonylurea), DPP-4i were not associated with any increase in cardiovascular risk for patients with T2DM [58]