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Description
These integrated systems go beyond simple co-delivery by enabling molecular-level coordination of metabolic, vascular, and immunologic responses

Their food intake can be normalized by the administration of physiological doses of -estradiol but not progesterone ( Menstrual cycle and eating disorders In addition to influencing food intake in healthy states, estradiol and progesterone have also been implicated in the etiology and expression of eating disorders ( It is interesting to speculate as to whether progesterone-only contraceptives could indirectly alter insulin sensitivity ( Gonadotropins and adiposity Although, gonadotropin hormone analogs have been used clinically for decades in assisted reproductive therapies and in the treatment of various infertility disorders ( Postmenopausal women have low estradiol, elevated FSH, concomitant bone loss, and increased body fat)

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R.et al (2017)
