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CARDIOVASCULAR EFFECTS OF GLP-1 RAs IN HUMAN STUDIES Blood pressure and heart rate Circulating biomarkers and lipid profiles Carotid intima-media thickness LV function and reperfusion injury in patients with coronary artery disease Retrospective studies on cardiovascular outcomes A prospective randomized clinical trial with primary cardiovascular outcome: the ELIXA study Preclinical and preliminary clinical evidence has consistently revealed potential cardiovascular benefits from the administration of GLP-1 RAs

Kidneys keep the bodys fluids filtered and balanced by removing liquid waste (called urea) and keeping water and important chemicals like sodium and potassium at the right levels
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It has not received FDA approval for weight loss or any other use