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These non-incretin metabolic peptides frequently exert effects on peripheral tissues such as skeletal muscle, adipose tissue, liver, and vasculature, and often engage receptors distinct from those targeted by current therapies
[DOI] [PMC free article] [PubMed] [Google Scholar] 81.Nozue T, Fukui K, Koyama Y, Fujii H, Kunishima T, Hikita H, et al
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Theyre present in the gut, but also in the brains reward-processing regions, the same pathways that govern cravings
