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In a 24-month RCT of newly diagnosed CFRD, repaglinide was demonstrated to be equivalent to insulin
Weight management medications in this class are generally used as long term treatments under ongoing medical care, not short crash courses
IBS symptoms can fluctuate over time and may worsen with age due to factors like stress, dietary changes, decreased physical activity, and hormonal changes

Because these drugs target separate metabolic pathways, they complement each other without directly competing for the same biological action