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References 1.Holst JJ
One is through AMPK or -catenin, which reduces lipid accumulation and prevents hepatocyte apoptosis
Despite knowledge of obesity-related complications in younger adults (increased risk of type 2 diabetes, liver and cardiovascular disease and malignancy), these considerations may be outweighed, in older adults, by concerns regarding weight-loss induced reduction in skeletal muscle and bone mass, and the awareness of the obesity paradox
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