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ClinicalTrials.gov (2022)

Early evidence suggests GLP-1s may reduce chronic inflammation and improve cellular function, supporting heart, liver, kidney, and brain health, and potentially lowering risk for obesity-related cancers

Annu Rev Nutr 41:4977 Qiu H, Novikov A, Vallon V (2017) Ketosis and diabetic ketoacidosis in response to SGLT2 inhibitors: Basic mechanisms and therapeutic perspectives

These benefits are particularly evident in conditions like nonalcoholic steatohepatitis (NASH), where GLP-1RAs alleviate inflammation and boost insulin sensitivity, leading to improved hepatic glucose management and reduced steatosis (Zheng et al., 2024)