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Limitations The major limitations of the studies that are included in this systematic review are the enrollment of healthy subjects and insufficient data in conditions that might affect pharmacokinetics (e.g., kidney dysfunction)

![Figure][1] Graphical Abstract: ### Competing Interest Statement The FR + FMG laboratory receives funding from AstraZeneca, Eli Lilly and LGM for unrelated research and FMG consults for Kallyope (New York)

The oral medication serves as an alternative to the injectable version.
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Online evaluation and US-licensed pharmacy.
