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Clinical Trial Evidence for Retatrutide The most widely referenced data comes from a Phase 2 trial published in the New England Journal of Medicine in 2023

2 = 0.009) (Figure 5 and Table 7)

The National Institute for Health and Care Excellence (NICE) provides clear, evidence-based guidance on managing high cholesterol, with statins remaining the first-line pharmacological treatment for most patients requiring lipid-lowering therapy

This success led to the development of exenatide, the first GLP-1 receptor agonist approved by the FDA for the treatment of diabetes (in 2004)
