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Of note, exendin-phe1 acted as a competitive antagonist against the -arrestin response to GLP-1 itself, suggesting that it might reduce the in vivo -arrestin recruitment by endogenous GLP-1 (Supplementary Fig

Related Stories Blood ketone threshold may help predict weight loss success New laser technology detects counterfeit alcohol through sealed bottles Study links semaglutide and tirzepatide to fewer anxiety and depression diagnoses in obesity care Simultaneously, a growing body of evidence suggests that Glucagon-Like Peptide-1 Receptor Agonists (GLP-1 RAs) are capable of crossing the blood-brain barrier (BBB) and interacting with the brain's reward and dopamine signaling regions, leading researchers to hypothesize that these originally weight-management-centric drugs could be used to address addictive behaviors, specifically regarding the suppression of ethanol-seeking triggers

E., Hameed, A., et al

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