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Weight loss drugs like Wegovy may lower the odds of developing an infection of the newly implanted joint in people undergoing hip replacement, new research finds.

Here, the authors show that remote ischaemic preconditioning releases the gut hormone GLP-1, which relaxes cardiac pericytes via KATP channels to reduce capillary constriction and no-reflow.

GLP-1 medications are prescribed for reasons beyond weight management, including type 2 diabetes, cardiovascular risk reduction, and metabolic health optimization