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295 In addition, high expression of TLR4 can increase H 2 O 2 production in the colonic mucosa of UC mice, induce redox activity in the mucosa, exacerbate oxidative stress, and promote the disease progression of UC

Unlike SGLT-2 inhibitors, GLP-1 receptor agonists can be used in patients with advanced-stage CKD or ESKD

In the hospital settings, the implementation of GLP-1RAs may be particularly challenging, especially with once-weekly formulations, due to the potential need for discontinuation before surgical or diagnostic procedures or in the event of clinical deterioration

Talk with your doctor ahead of time to find out what they recommend