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Glucagon-like peptide-1 (GLP-1) is a gut-derived hormone essential for maintaining glucose homeostasis through multiple physiological pathways: triggering insulin release, inhibiting glucagon secretion, delaying gastric emptying, enhancing feelings of fullness, and suppressing appetite

"We haven't scratched the surface in terms of how big the [GLP-1 weight loss] drugs are going to get," Mizuho strategist Jared Holz said.

Lawsuits over severe side effects from taking GLP-1 medications Ozempic, Wegovy, Mounjaro, Trulicity, and Rybelsus

With GLP1 therapeutics entering their second wave of innovation, this is a pivotal moment for teams pushing boundaries in metabolic and neuroendocrine drug development