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Description
Alleviation of depression by glucagonlike peptide 1 through the regulation of neuroinflammation, neurotransmitters, neurogenesis, and synaptic function
The ACHIEVE-3 head-to-head data favor orforglipron on both efficacy and convenience endpoints

Like any medication, GLP-1 receptor agonists come with potential side effects
These approaches can be used alongside any other strategy, including GLP-1 therapy after weaning, and often improve long-term outcomes by addressing root causes rather than just symptoms
