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GLP-1RAs such as liraglutide and exenatide decrease pro-inflammatory cytokines, tumor necrosis factor-alpha ( TNF- ), and interleukin-1 (IL-18) in rodent mouse models of diabetic neuropathy [69,70]
Transcriptomics in peripheral tissues Bulk RNA sequencing showed that GLP-1GIPLani robustly induced anti-inflammatory gene programmes in the liver and skeletal muscle (Fig
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The most common side effects patients report are nausea (55%), diarrhea (12%), and stomach pain (9%)
