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In clinical trials, Mounjaro at its highest dose has shown slightly higher average weight loss than Wegovy at its highest dose (22.5% vs 20.7% at 72 weeks)

The GLP-1 pathway signals fullness and reduces hunger, while the GIP pathway enhances insulin sensitivity and metabolic function

doi: 10.1016/j.jemrpt.2025.100139 14 SoodNBansalOGargRHoskoteA

On phentermine a lot of the weight loss happens toward the beginning of treatment
