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Description
Metformin is a biguanide that primarily reduces hepatic glucose production and improves insulin sensitivity in peripheral tissues without causing hypoglycaemia
Furthermore, previous clinical studies have often suffered from small sample sizes or limited medical databases, thereby restricting their broader generalizability and use as proxies for performance estimates in routine clinical practice
Individual responses vary based on baseline A1C, dose level, adherence, and lifestyle factors
The dual-receptor mechanism means hunger signals quiet faster than with traditional GLP-1 monotherapy
