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If you have rheumatoid arthritis and are considering compounded GLP-1 therapy for metabolic or weight-related comorbidities, this genetic context can support a deeper conversation with your provider about safety, potential off-label anti-inflammatory effects, and how to monitor disease activity alongside any new treatment

While there have been no previous cases of dermal hypersensitivity reactions to semaglutide reported in the literature, there have been reported cases for other drugs in the GLP-1 receptor agonist class

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