glp 1 and kidney GLP-1 agonists in the treatment of chronic disease in type 2 diabetes obesity GLP1 Receptor Agonists vs SGLT2-I
Description
Nevertheless, GLP-1 presented a rather ephemeral circulatory half-life, lasting a mere 12 min, due to the rapid enzymatic degradation by dipeptidyl peptidase IV (DPP-4), which markedly limits its biological efficacy [35]

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Endocrinology and Metabolism, 289 (6), E1015E1022

The FDA's updated guidance underscores the importance of presenting benefit and risk information together, especially on platforms with character limitations
