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Description
Once-weekly semaglutide has shown a 26% reduction in risk of major adverse CV events (MACE) in SUSTAIN 6 [34], and dulaglutide has been investigated in REWIND with a 12% reduction in risk of MACE [35]
GLP-1 receptors that initially respond strongly to the agonist gradually calibrate their sensitivity

What clinical evidence supports increasing my semaglutide dose during a plateau
The effects of semaglutide continue as long as the medication is used regularly and accompanied by a healthy lifestyle.
