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Accessible as injectable and oral forms, including the well-known brands Wegovy and Ozempic, semaglutide helps control appetite and manage blood sugar over prolonged periods

doi:10.1007/s00592-020-01533-5 65

First, some of the muscle change happens with any rapid weight loss, and a portion may be a normal adjustment to a smaller body rather than harmful wasting (Mocciaro and colleagues, BMJ Nutrition Prevention and Health , 2025)

Poor sleep increases cortisol and ghrelin (hunger hormone) production, which can blunt medication effects
