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Description
Under the per-protocol approach, censoring events included discontinuation (no prescription of the index drug recorded within 90 days) and switching (prescription of the comparator drug)
Phentermine typically shows effectiveness for 12 weeks or less before tolerance develops, limiting its long-term application in chronic weight management
doi: 10.1016/j.drudis.2016.01.016 66 GimenoD.KivimakiM.BrunnerE
Water retention from sodium, hormones, travel, or even a hard workout can temporarily mask fat loss
