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While clinical trials report gastrointestinal symptoms in 1544% of users, formally diagnosed gastroparesis appears uncommon

Frederich R, Alexander JH, Fiodereck FT et al

A flexible segment in DPP-4 connects the transmembrane domain to the extracellular domain and is the target of shedding, a process in which the enzyme is cleaved and released into circulation [22]

Thus, even with progress in pharmacological weight loss, there remains a significant unmet need for obesity treatment