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It must be used alongside a reduced-calorie diet and increased physical activity

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Prioritise overall wellbeing: Maintain regular physical activity, which improves cardiovascular health, mood, and sexual function Ensure adequate sleep (79 hours nightly), as sleep deprivation significantly impacts libido Manage stress through relaxation techniques, mindfulness, or counselling if needed Allow time for physical intimacy even when spontaneous desire is reducedresponsive desire often develops during intimate activity Be aware of contraception needs

Importantly, semaglutide is not indicated for the treatment of type 1 diabetes mellitus or diabetic ketoacidosis, and should not be used concurrently with other GLP-1 receptor agonists