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Whilst research suggests potential benefits, the evidence base has important limitations that must be acknowledged

Alcohol is not contraindicated with tirzepatide, but GLP-1 medications can alter alcohol tolerance and gastric emptying

According to the American Association of Clinical Endocrinologists and American College of Endocrinology (AACE/ACE) Obesity Clinical Practice Guidelines, weight loss medications should be offered as chronic treatment along with lifestyle modifications to patients with obesity when the potential benefits outweigh the risks

Men who want to start a family get the best results when they combine these medications with healthy habits, staying active, eating nutritious foods, and managing stress