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In late-stage trials, people taking orforglipron lost an average of about 12% of their body weight over roughly 72 weeks , and head-to-head studies suggest it may outperform standard oral semaglutide tablets (Rybelsus) in both weight loss and blood sugar control

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So it was very frustrating to do all the same things and never be able to change that number on the scale or the way my body looked," she continued.

The future of GLP-1RAs in anti-inflammatory therapy looks promising, with ongoing research aiming to optimize their therapeutic use, develop patient-specific treatment paradigms, and explore novel applications