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However, several studies failed to reveal an effect of GLP(1-37) to increase insulin secretion and its function was unclear (1)

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RNA isolation and gene expression Jejunal RNA was isolated with TRIzol Reagent (Ambion) as per the manufacturers protocol and reverse transcribed using a High-Capacity cDNA Reverse Transcription Kit (Fisher Scientific 43-688-14)

Furthermore, GLP1Rs, like numerous other transmembrane proteins, may initiate signalling through interactions with other proteins on the liver cell's surface or within the cell, thereby triggering a sequence of events that result in diverse cellular response processes
