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Science 361 (6408)

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Its unique triple-agonist mechanism targeting GLP-1, GIP, and glucagon receptors positions it as a powerhouse in metabolic research

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Neurotensin levels are correlated with leptin (218), rise in response to fatty meals, signals through two different G-protein coupled receptors known as NTSR1 and 2, and a third single transmembrane receptor, NTSR3, also known as sortilin (219)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 8.Bang-Berthelsen CH, et al

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