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Description
In the perioperative management of patients taking SGLT2 inhibitors, the optimal approach for preventing EDKA is to withhold the medication in any setting where predisposing factors for ketoacidosis are present (e.g

44 With C-terminal curtailing, the insulinotropic activity of exenatide gradually declines

Pre-mixed combination products like Soliqua (insulin glargine plus lixisenatide) and Xultophy (insulin degludec plus liraglutide) simplify this approach into a single injection

These benefits include reduced risk of heart attack, stroke, and cardiovascular death in people with type 2 diabetes
