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However, when targeted in a controlled way, glucagon receptor activation can promote energy expenditure by stimulating the breakdown of stored fat and encouraging lipolysis (fat breakdown)

41 As discussed above, mitochondrial dysfunction (mitochondrial bioenergetics, calcium buffering) and mitochondrial quality control systems (mitochondrial dynamics, mitophagy, mitochondrial biogenesis) may be involved in the pathological mechanisms of diabetes-related NDs

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It is essential to consult with our healthcare professionals to determine the best treatment plan for your specific circumstances.