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Importantly, tirzepatide can reduce the exposure to oral contraceptives after initiation and dose escalation
This means that every patient will have different doses depending on their response and tolerance to the starting dose

This makes it much easier to eat smaller portions and avoid the constant urge to snack throughout the day

If fatigue is persistent after the adaptation period, check whether total caloric intake has dropped below approximately 1,200 to 1,400 calories per day (the minimum for most people to maintain energy and lean mass)
