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Similarly, IL-6 levels were significantly reduced with tirzepatide at 5 mg (MD: 18.8
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Initially approved for diabetes treatment under the name Ozempic, it became a recognized treatment for obesity as Wegovy
Our results reveal the existence of residue networks crucial for unimolecular agonist-mediated receptor activation and their distinct signaling patterns, which might be useful to the rational design of biased drug leads.
