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GLP-1 receptor agonists increase resting heart rate

140,141 This synergistic impact on both the metabolic and genetic aspects of aging makes GLP-1 RAs a distinctive approach to postpone cellular aging and encourage longevity

Despite its effectiveness, the drug's gastrointestinal side effects due to its action on gastrointestinal lipases can affect patient compliance [40]

Severe kidney impairment (eGFR below 15 mL/min/1.73m) requires specialized medical evaluation before starting