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In clinical trials, patients lost 12 percent of their body weight on average, in line with the original Ozempic injection, but a smidge lower than Mounjaro, Zepbound, and some of the more recent entries into this drug class

The company has now added compounded GLP-1 injections with the same active ingredient as buzzy branded weight loss drugs Ozempic and Wegovy, executives said

This approval was significant because it marked the first time since 2014 that the FDA had approved a new drug for this purpose

Another approach to prolong GLP-1 action in vivo is DPP-IV inhibitors, since DPP-IV is one of the main causes of GLP-1 degradation