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You should contact your doctor or seek emergency medical care if you experience any of the following symptoms during your first week (or at any point during your treatment): Severe and Persistent Abdominal Pain: If you experience intense, unyielding pain in your upper abdomen that radiates to your back, with or without vomiting, you must contact your doctor immediately

Dapagliflozin Initial Combination Therapy with Metformin HCl Extended-Release A total of 1236 treatment-naive adult patients with inadequately controlled type 2 diabetes mellitus (HbA1c 7.5% and 12%) participated in 2 active-controlled trials of 24-week duration to evaluate initial therapy with dapagliflozin 5 mg (NCT00643851) or 10 mg (NCT00859898) in combination with metformin extended-release formulation

They may ask the following When did your rectal bleeding start