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Click here to listen to this article Share via Key Facts The Rule of 20-30%: In typical weight loss, approximately 20-30% of mass lost is lean tissue (muscle/bone/water), not just fat

12.2 Personal or Family History of Medullary Thyroid Carcinoma Semaglutide shouldn't be given to people who have had medullary thyroid carcinoma in the past

There could be extra rare or serious adverse effects, just like with any medication

This can lead to denial at renewal because the insurer cannot confirm ongoing clinical effectiveness
