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Bupropion produced a positive response (two to three times control mutation rate) in two of five strains in the Ames bacterial mutagenicity test and an increase in chromosomal aberrations in one of three in vivo rat bone marrow cytogenetic studies
If you are trying to figure out which one is strongest, which one is safest, and whether any of this applies to you, here is what the research actually shows

[DOI] [PubMed] [Google Scholar] Otonkoski T, Hayek A

It works through an entirely different mechanism, blocking the SGLT2 protein in the kidneys that would normally reabsorb glucose back into the bloodstream
