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Description
Beta-cell-targeted overexpression of phosphodiesterase 3B in mice causes impaired insulin secretion, glucose intolerance, and deranged islet morphology

As a result, simply injecting GLP-1 itself was impractical it would be cleared before having sustained benefit

The Precision Peptide Genetic Test ($99 add-on after month one) analyzes 14 metabolic pathways, including variants that control blood pressure regulation, fluid balance, and GI motility

[DOI] [PMC free article] [PubMed] [Google Scholar] 48.Silveira SQ, et al
