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Positive and negative outcome analyses We then performed positive outcome analyses, and found markedly increased rates of nausea after GLP-1 RAs treatment (aHR: 1.47, 95% CI 1.33-1.62) as a reported complication

We report herein a series of pharmacological and molecular studies in two validated mouse models of PCOS, generated by gestational (PNA) or postweaning (PWA) androgenization, addressing the effects of GLP1-based multi-agonist therapies on metabolic and reproductive traits of PCOS