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Common adverse effects include gastrointestinal symptoms such as nausea, vomiting, diarrhoea, and constipation, which typically diminish over time

No animals met predefined humane endpoint criteria requiring unscheduled euthanasia in either study

They tend to have a slightly grainier texture, which matters more than you'd think on days when your stomach is already unsettled

If you want to see how semaglutide steps up over time, this semaglutide dosing chart gives a clear visual of titration and maintenance
