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The same finding had been reported by a prior larger meta-analysis (6,914 patients with overweight or obesity and T2DM) over 8 studies 184,185,189,190,191,192,193,194 , but only when the largest study that also included non-diabetic participants 193 was excluded in a sensitivity analysis 195

The Importance of Addressing Weight Problems Excess weight can increase your risk for several serious health issues such as type 2 diabetes, heart disease, sleep apnea, high blood pressure, joint problems, and certain types of cancer

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To date, the only treatment proved to be effective in NAFLD is a weight loss of 710%, able to significantly improve the histological grade of fibrosis and steatosis, in addition to hepatic cytolysis [7,8]