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Studies in humans are limited, poorly designed, and show inconsistent results 22 Ooi, C.P
In cardiac remodeling, cardiomyocytes in a failing heart undergo maladaptive changes including abnormalities in gene expression, mechanical properties, metabolic pathways, and the extracellular matrix (ECM) 28
Other animal studies have found that GLP-1R agonists reduce amphetamine use and amphetamine-induced hyperlocomotion
(5.4) Acute Kidney Injury Due to Volume Depletion: Monitor renal function in patients with renal impairment reporting adverse reactions that could lead to volume depletion
